How to compare instrumental variable and conventional regression analyses using negative controls and bias plots
نویسندگان
چکیده
منابع مشابه
How to compare instrumental variable and conventional regression analyses using negative controls and bias plots
There is increasing interest in the use of instrumental variable analysis to overcome unmeasured confounding in observational pharmacoepidemiological studies. This is partly because instrumental variable analyses are potentially less biased than conventional regression analyses. However, instrumental variable analyses are less precise, and regulators and clinicians find it difficult to interpre...
متن کاملInstrumental Variable Quantile Regression * †
Quantile regression is an increasingly important tool that estimates the conditional quantiles of a response Y given a vector of regressors D. It usefully generalizes Laplace’s median regression and can be used to measure the effect of covariates not only in the center of a distribution, but also in the upper and lower tails. For the linear quantile model defined by Y = D′γ(U) where D′γ(U) is s...
متن کاملDoubly Robust Instrumental Variable Regression
Instrumental variable (IV) estimation typically requires the user to correctly specify the relationship between the regressors and the outcome to obtain a consistent estimate of the effects of the treatments. This paper proposes doubly robust IV regression estimators that only require the user to either correctly specify the relationship between the measured confounding variables (i.e., include...
متن کاملcomparative dna interaction studies of antiviral drug, zidovudine and its complex using different instrumental methods
هدف از این مطالعه بررسی امکان استفاده از داروهای شناخته شده در درمان سایر بیماریها به عنوان داروهای ضد سرطان است. همچنین با استفاده از این داروها در ساختمان کمپلکس فلز می توان شاخص های دارویی بدست آمده را بررسی نمود. داروی ضد ویروس ایدز(hiv)به نام زیدوودین(azt)انتخاب و.کمپلکس.محلول.در.آب[pt(azt)2]cl2سنتزو به روشهای مختلف فیزیکی و شیمیایی شناسایی گردید. بر هم کنش مقایسه ای این دارو و کمپلکس پلا...
15 صفحه اولOracle Inequality for Instrumental Variable Regression
where φ is the parameter of interest which models the relationship while U is an error term. Contrary to usual statistical regression models, the error term is correlated with the explanatory variables X, hence E(U |X) 6= 0, preventing direct estimation of φ. To overcome the endogeneity of X, we assume that there exists an observed random variable W , called the instrument, which decorrelates t...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Epidemiology
سال: 2017
ISSN: 0300-5771,1464-3685
DOI: 10.1093/ije/dyx014